Kiwi Syslog Mail error: SMTP protocol error. 421 4.3.2 Service not available

I am trying to setup the email section of the Kiwi Syslog server and I am receiving the following error in the log, "Mail error: SMTP protocol error. 421 4.3.2 Service not available.". Does this message mean I need to have the SMTP service installed on the same server as the Kiwi Syslog server? Or is this error coming from the server I entered as the valid SMTP server? The admin manual does not specify.

Thanks,

Caleb

Kiwi Syslog Server Version 9.4.1

Windows Server 2008 R2 Standard